Interaction with Grb14 results in site-specific regulation of tyrosine phosphorylation of the insulin receptor

The dynamics of interaction of the insulin receptor (IR) with Grb14 was monitored, in real time, in living human embryonic kidney cells, using bioluminescence resonance energy transfer (BRET). We observed that insulin rapidly and dose-dependently stimulated this interaction. We also observed that in...

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Bibliografiska uppgifter
Huvudupphovsmän: Nouaille, Sébastien, Blanquart, Christophe, Zilberfarb, Vladimir, Boute, Nicolas, Perdereau, Dominique, Roix, Johan, Burnol, Anne-Françoise, Issad, Tarik
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
Ämnen:
Scientific Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479551/
https://ncbi.nlm.nih.gov/pubmed/16582879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400668
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