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Human cytomegalovirus prevents replication licensing by inhibiting MCM loading onto chromatin
To allow DNA replication only once per cell cycle, origins of replication are reactivated ('licensed') during each G1 phase. Licensing is facilitated by assembly of the pre-replicative complex (pre-RC) at origins that concludes with loading the mini-chromosome maintenance (MCM) complex ont...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1315807/ https://ncbi.nlm.nih.gov/pubmed/12524519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor707 |
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