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Inhibition of Human Cytomegalovirus Immediate-Early Gene Expression by Cyclin A2-Dependent Kinase Activity

Human cytomegalovirus (HCMV) starts its lytic replication cycle only in the G(0)/G(1) phase of the cell division cycle. S/G(2) cells can be infected but block the onset of immediate-early (IE) gene expression. This block can be overcome by inhibition of cyclin-dependent kinases (CDKs), suggesting th...

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Detalhes bibliográficos
Main Authors: Oduro, Jennifer D., Uecker, Ralf, Hagemeier, Christian, Wiebusch, Lüder
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416125/
https://ncbi.nlm.nih.gov/pubmed/22718829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.07181-11
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