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Time-resolved fluorescence of 2-aminopurine as a probe of base flipping in M.HhaI–DNA complexes
DNA base flipping is an important mechanism in molecular enzymology, but its study is limited by the lack of an accessible and reliable diagnostic technique. A series of crystalline complexes of a DNA methyltransferase, M.HhaI, and its cognate DNA, in which a fluorescent nucleobase analogue, 2-amino...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1310896/ https://ncbi.nlm.nih.gov/pubmed/16340006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki995 |
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