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The Src family kinase Hck couples BCR/ABL to STAT5 activation in myeloid leukemia cells
Signal transducer and activator of transcription 5 (STAT5) is constitutively activated by BCR/ABL, the oncogenic tyrosine kinase responsible for chronic myelogenous leukemia. The mechanism of BCR/ABL-mediated STAT5 activation is unknown. We show here that the BCR/ABL SH3 and SH2 domains interact wit...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC131059/ https://ncbi.nlm.nih.gov/pubmed/12411494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf562 |
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