Protein Tyrosine Phosphatase 1B Antagonizes Signalling by Oncoprotein Tyrosine Kinase p210 bcr-abl In Vivo

The p210 bcr-abl protein tyrosine kinase (PTK) appears to be directly responsible for the initial manifestations of chronic myelogenous leukemia (CML). In contrast to the extensive characterization of the PTK and its effects on cell function, relatively little is known about the nature of the protei...

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Bibliographic Details
Main Authors: LaMontagne, Kenneth R., Flint, Andrew J., Franza, B. Robert, Pendergast, Ann Marie, Tonks, Nicholas K.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC110676/
https://ncbi.nlm.nih.gov/pubmed/9566916
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