載入...

The Src family kinase Hck couples BCR/ABL to STAT5 activation in myeloid leukemia cells

Signal transducer and activator of transcription 5 (STAT5) is constitutively activated by BCR/ABL, the oncogenic tyrosine kinase responsible for chronic myelogenous leukemia. The mechanism of BCR/ABL-mediated STAT5 activation is unknown. We show here that the BCR/ABL SH3 and SH2 domains interact wit...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Klejman, Agata, Schreiner, Steven J., Nieborowska-Skorska, Malgorzata, Slupianek, Artur, Wilson, Matthew, Smithgall, Thomas E., Skorski, Tomasz
格式: Artigo
語言:Inglês
出版: Oxford University Press 2002
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC131059/
https://ncbi.nlm.nih.gov/pubmed/12411494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf562
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!