Llwytho...

Distinct involvement of the Jun-N-terminal kinase and NF-κB pathways in the repression of the human COL1A2 gene by TNF-α

We used a gene knockout approach to elucidate the specific roles played by the Jun-N-terminal kinase (JNK) and NF-κB pathways downstream of TNF-α in the context of α(2) type I collagen gene (COL1A2) expression. In JNK(1)(−/−)-JNK(2)(−/−) (JNK(−/−)) fibroblasts, TNF-α inhibited basal COL1A2 expressio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Verrecchia, Franck, Wagner, Erwin F., Mauviel, Alain
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2002
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307596/
https://ncbi.nlm.nih.gov/pubmed/12393755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf219
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