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p53 and DNA damage-inducible expression of the xeroderma pigmentosum group C gene
The p53 tumor suppressor gene product is a transcription factor involved in cell-cycle regulation, apoptosis, and DNA repair. We and others have shown that p53 is required for efficient nucleotide excision repair (NER) of UV-induced DNA lesions. p53-deficient cells are defective in the repair of UV...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The National Academy of Sciences
2002
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC130573/ https://ncbi.nlm.nih.gov/pubmed/12242345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.202485699 |
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