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p53 and DNA damage-inducible expression of the xeroderma pigmentosum group C gene

The p53 tumor suppressor gene product is a transcription factor involved in cell-cycle regulation, apoptosis, and DNA repair. We and others have shown that p53 is required for efficient nucleotide excision repair (NER) of UV-induced DNA lesions. p53-deficient cells are defective in the repair of UV...

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Autors principals: Adimoolam, Shanthi, Ford, James M.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC130573/
https://ncbi.nlm.nih.gov/pubmed/12242345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.202485699
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