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p48 Activates a UV-Damaged-DNA Binding Factor and Is Defective in Xeroderma Pigmentosum Group E Cells That Lack Binding Activity

A subset of xeroderma pigmentosum (XP) group E cells lack a factor that binds to DNA damaged by UV radiation. This factor can be purified to homogeneity as p125, a 125-kDa polypeptide. However, when cDNA encoding p125 is translated in vitro, only a small fraction binds to UV-damaged DNA, suggesting...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Hwang, Byung Joon, Toering, Stephanie, Francke, Uta, Chu, Gilbert
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1998
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109023/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9632823/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.7.4391
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