Concentration-Dependent Realignment of the Antimicrobial Peptide PGLa in Lipid Membranes Observed by Solid-State (19)F-NMR

The membrane-disruptive antimicrobial peptide PGLa is found to change its orientation in a dimyristoyl-phosphatidylcholine bilayer when its concentration is increased to biologically active levels. The alignment of the α-helix was determined by highly sensitive solid-state NMR measurements of (19)F...

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Hlavní autoři: Glaser, Ralf W., Sachse, Carsten, Dürr, Ulrich H. N., Wadhwani, Parvesh, Afonin, Sergii, Strandberg, Erik, Ulrich, Anne S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2005
Témata:
Membranes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305486/
https://ncbi.nlm.nih.gov/pubmed/15695635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.056424
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