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Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins
This paper describes insig-2, a second protein of the endoplasmic reticulum that blocks the processing of sterol regulatory element-binding proteins (SREBPs) by binding to SCAP (SREBP cleavage-activating protein) in a sterol-regulated fashion, thus preventing it from escorting SREBPs to the Golgi. B...
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主要な著者: | , , |
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フォーマット: | Artigo |
言語: | Inglês |
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The National Academy of Sciences
2002
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC130532/ https://ncbi.nlm.nih.gov/pubmed/12242332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162488899 |
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