β-Globin mRNA decay in erythroid cells: UG site-preferred endonucleolytic cleavage that is augmented by a premature termination codon
Previous work showed that human β-globin mRNAs harboring a premature termination codon are degraded in the erythroid tissues of mice to products that lack sequences from the mRNA 5′ end but contain a 5′ cap-like structure. Whether these decay products are the consequence of endonucleolytic or 5′-to-...
Kaydedildi:
| Yayımlandı: | Proc Natl Acad Sci U S A |
|---|---|
| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2002
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC130530/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12242335/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.192442399 |
| Etiketler: |
Etiket eklenmemiş, İlk siz ekleyin!
|