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The Transmembrane Domain of the Acetylcholine Receptor: Insights from Simulations on Synthetic Peptide Models

We have studied the structure and properties of a bundle of α-helical peptides embedded in a 1,2-dimyristoyl-3-phosphatidylcholine phospholipid bilayer by molecular dynamics simulations. The bundle of five transmembrane δM2 segments constitutes the model for the pore region of the nicotinic acetylch...

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Bibliografiske detaljer
Main Authors: Saiz, Leonor, Klein, Michael L.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305168/
https://ncbi.nlm.nih.gov/pubmed/15556982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.049726
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