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Modeling P-Loops Domain of Sodium Channel: Homology with Potassium Channels and Interaction with Ligands

A large body of experimental data on Na(+) channels is available, but the interpretation of these data in structural terms is difficult in the absence of a high-resolution structure. Essentially different electrophysiological and pharmacological properties of Na(+) and K(+) channels and poor identit...

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Autors principals: Tikhonov, Denis B., Zhorov, Boris S.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304997/
https://ncbi.nlm.nih.gov/pubmed/15475578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.048173
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