KvAP-Based Model of the Pore Region of Shaker Potassium Channel Is Consistent with Cadmium- and Ligand-Binding Experiments

Potassium channels play fundamental roles in excitable cells. X-ray structures of bacterial potassium channels show that the pore-lining inner helices obstruct the cytoplasmic entrance to the closed channel KcsA, but diverge in widely open channels MthK and KvAP, suggesting a gating-hinge role for a...

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Hlavní autoři: Bruhova, Iva, Zhorov, Boris S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2005
Témata:
Channels, Receptors, and Electrical Signaling
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366588/
https://ncbi.nlm.nih.gov/pubmed/15908577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.062240
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