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A homology model of the pore domain of a voltage-gated calcium channel is consistent with available SCAM data

In the absence of x-ray structures of calcium channels, their homology models are used to rationalize experimental data and design new experiments. The modeling relies on sequence alignments between calcium and potassium channels. Zhen et al. (2005. J. Gen. Physiol. doi:10.1085/jgp.200509292) used t...

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Main Authors: Bruhova, Iva, Zhorov, Boris S.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828909/
https://ncbi.nlm.nih.gov/pubmed/20176854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910288
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