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Two Complementary, Local Excitation, Global Inhibition Mechanisms Acting in Parallel Can Explain the Chemoattractant-Induced Regulation of PI(3,4,5)P(3) Response in Dictyostelium Cells

Chemotaxing cells, such as Dictyostelium and mammalian neutrophils, sense shallow chemoattractant gradients and respond with highly polarized changes in cell morphology and motility. Uniform chemoattractant stimulation induces the transient translocations of several downstream signaling components,...

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書誌詳細
主要な著者: Ma, Lan, Janetopoulos, Chris, Yang, Liu, Devreotes, Peter N., Iglesias, Pablo A.
フォーマット: Artigo
言語:Inglês
出版事項: Biophysical Society 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304889/
https://ncbi.nlm.nih.gov/pubmed/15465874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.045484
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