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Distinct Effects on Ca(2+) Handling Caused by Malignant Hyperthermia and Central Core Disease Mutations in RyR1
Malignant hyperthermia (MH) and central core disease (CCD) are disorders of skeletal muscle Ca(2+) homeostasis that are linked to mutations in the type 1 ryanodine receptor (RyR1). Certain RyR1 mutations result in an MH-selective phenotype (MH-only), whereas others result in a mixed phenotype (MH +...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1304789/ https://ncbi.nlm.nih.gov/pubmed/15347586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.048447 |
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