Crystallization Mechanisms of Hemoglobin C in the R State

Crystallization of the mutated hemoglobin, HbC, which occurs inside red blood cells of patients expressing β(C)-globin and exhibiting the homozygous CC and the heterozygous SC (in which two mutant β-globins, S and C, are expressed) diseases, is a convenient model for processes underlying numerous co...

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Bibliographic Details
Main Authors: Feeling-Taylor, Angela R., Yau, S.-T., Petsev, Dimiter N., Nagel, Ronald L., Hirsch, Rhoda Elison, Vekilov, Peter G.
Format: Artigo
Language:Inglês
Published: Biophysical Society 2004
Subjects:
Proteins
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304680/
https://ncbi.nlm.nih.gov/pubmed/15454456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.039743
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