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Liganded Hemoglobin Structural Perturbations by the Allosteric Effector L35

Effector binding to liganded hemoglobin (Hb) provides a new understanding of structural determinants of Hb function. L35, a bezafibrate-related compound, is one of the more potent synthetic regulators of Hb oxygen (O(2)) affinity. In the presence of inositol hexaphosphate and bezafibrate (or derivat...

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Detalhes bibliográficos
Main Authors: Chen, Qiuying, Lalezari, Iraj, Nagel, Ronald L., Hirsch, Rhoda Elison
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305258/
https://ncbi.nlm.nih.gov/pubmed/15626716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.046136
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