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In Silico Activation of KcsA K(+) Channel by Lateral Forces Applied to the C-Termini of Inner Helices
Crystallographic studies of K(+) channels in the closed (KcsA) and open (MthK) states suggest that Gly(99) (KcsA numbering) in the inner helices serves as a gating hinge during channel activation. However, some P-loop channels have larger residues in the corresponding position. The comparison of x-r...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Biophysical Society
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1304559/ https://ncbi.nlm.nih.gov/pubmed/15345533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.037770 |
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