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The External K(+) Concentration and Mutations in the Outer Pore Mouth Affect the Inhibition of Kv1.5 Current by Ni(2+)
By examining the consequences both of changes of [K(+)](o) and of point mutations in the outer pore mouth, our goal was to determine if the mechanism of the block of Kv1.5 ionic currents by external Ni(2+) is similar to that for proton block. Ni(2+) block is inhibited by increasing [K(+)](o), by mut...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Biophysical Society
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1304074/ https://ncbi.nlm.nih.gov/pubmed/15041663 |
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