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Functional Influence of the Pore Helix Glutamate in the KcsA K(+) Channel
The E71 residue is buried near the selectivity filter in the KcsA K(+) channel and forms a carboxyl-carboxylate bridge with D80. We have investigated the importance of E71 by examining neutralization mutants at this position using biochemical and electrophysiological methods. E71 mutations different...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Biophysical Society
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1304065/ https://ncbi.nlm.nih.gov/pubmed/15041654 |
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