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Restoration of Single-Channel Currents Using the Segmental k-Means Method Based on Hidden Markov Modeling
Patch-clamp recording provides an unprecedented means for study of detailed kinetics of ion channels at the single molecule level. Analysis of the recordings often begins with idealization of noisy recordings into continuous dwell-time sequences. Success of an analysis is contingent on accuracy of t...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Biophysical Society
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1303984/ https://ncbi.nlm.nih.gov/pubmed/14990476 |
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