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Restoration of Single-Channel Currents Using the Segmental k-Means Method Based on Hidden Markov Modeling

Patch-clamp recording provides an unprecedented means for study of detailed kinetics of ion channels at the single molecule level. Analysis of the recordings often begins with idealization of noisy recordings into continuous dwell-time sequences. Success of an analysis is contingent on accuracy of t...

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Hlavní autor: Qin, Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303984/
https://ncbi.nlm.nih.gov/pubmed/14990476
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