Activity and Structural Comparisons of Solution Associating and Monomeric Channel-Forming Peptides Derived from the Glycine Receptor M2 Segment

A number of channel-forming peptides derived from the second transmembrane (TM) segment (M2) of the glycine receptor α(1) subunit (M2GlyR), including the 22-residue sequence NK(4)-M2GlyR p22 wild type (WT) (KKKKPARVGLGITTVLTMTTQS), induce anion permeation across epithelial cell monolayers. In vitro...

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Detalhes bibliográficos
Main Authors: Cook, Gabriel A., Prakash, Om, Zhang, Ke, Shank, Lalida P., Takeguchi, Wade A., Robbins, Ashley, Gong, Yu-Xi, Iwamoto, Takeo, Schultz, Bruce D., Tomich, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Channels, Receptors, and Transporters
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303979/
https://ncbi.nlm.nih.gov/pubmed/14990471
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