Structural Characterization of Two Pore-Forming Peptides: Consequences of Introducing a C-Terminal Tryptophan

Synthetic channel-forming peptides that can restore chloride conductance across epithelial membranes could provide a novel treatment of channelopathies such as cystic fibrosis. Among series of 22-residue peptides derived from the second transmembrane segment of the glycine receptor α(1)-subunit (M2G...

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Main Authors: Herrera, Alvaro I., Al-Rawi, Ahlam, Cook, Gabriel A., Gao, Jian, Iwamoto, Takeo, Prakash, Om, Tomich, John M., Chen, Jianhan
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909830/
https://ncbi.nlm.nih.gov/pubmed/20544961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22736
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