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Structural and biophysical properties of a synthetic channel-forming peptide: Designing a clinically relevant anion selective pore

The design, synthesis, modeling and in vitro testing of channel-forming peptides derived from the cys-loop superfamily of ligand-gated ion channels are part of an ongoing research focus. Over 300 different sequences have been prepared based on the M2 transmembrane segment of the spinal cord glycine...

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Main Authors: Bukovnik, U., Gao, J., Cook, J.,G.A., Shank, L.P., Seabra, M.B., Schultz, B.D., Iwamoto, T., Chen, J., Tomich, J.M.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245884/
https://ncbi.nlm.nih.gov/pubmed/21835162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2011.07.037
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