Redesigning Channel-Forming Peptides: Amino Acid Substitutions that Enhance Rates of Supramolecular Self-Assembly and Raise Ion Transport Activity

Three series of 22-residue peptides derived from the transmembrane M2 segment of the glycine receptor α1-subunit (M2GlyR) have been designed, synthesized, and tested to determine the plasticity of a channel-forming sequence and to define whether channel pores with enhanced conductive properties coul...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Shank, Lalida P., Broughman, James R., Takeguchi, Wade, Cook, Gabriel, Robbins, Ashley S., Hahn, Lindsey, Radke, Gary, Iwamoto, Takeo, Schultz, Bruce D., Tomich, John M.
Format: Artigo
Idioma:Inglês
Publicat: Biophysical Society 2006
Matèries:
Supramolecular Assemblies
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386792/
https://ncbi.nlm.nih.gov/pubmed/16387776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.070078
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars