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Sensitivity, Specificity, and the Hybridization Isotherms of DNA Chips

Competitive hybridization, at the surface and in the bulk, lowers the sensitivity of DNA chips. Competitive surface hybridization occurs when different targets can hybridize with the same probe. Competitive bulk hybridization takes place when the targets can hybridize with free complementary chains...

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Detalhes bibliográficos
Main Authors: Halperin, A., Buhot, A., Zhulina, E.B.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303922/
https://ncbi.nlm.nih.gov/pubmed/14747310
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