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Brush Effects on DNA Chips: Thermodynamics, Kinetics, and Design Guidelines
In biology experiments, oligonucleotide microarrays are contacted with a solution of long nucleic acid targets. The hybridized probes thus carry long tails. When the surface density of the oligonucleotide probes is high enough, the progress of hybridization gives rise to a polyelectrolyte brush due...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366630/ https://ncbi.nlm.nih.gov/pubmed/15908581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.063479 |
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