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Modeling the Binding Sites of Anti-Hen Egg White Lysozyme Antibodies HyHEL-8 and HyHEL-26: An Insight into the Molecular Basis of Antibody Cross-Reactivity and Specificity

Three antibodies, HyHEL-8 (HH8), HyHEL-10 (HH10), and HyHEL-26 (HH26) are specific for the same epitope on hen egg white lysozyme (HEL), and share >90% sequence homology. Their affinities vary by several orders of magnitude, and among the three antibodies, HH8 is the most cross-reactive with kine...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Mohan, S., Sinha, Neeti, Smith-Gill, Sandra J.
פורמט: Artigo
שפה:Inglês
יצא לאור: Biophysical Society 2003
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303598/
https://ncbi.nlm.nih.gov/pubmed/14581222
תגים: הוספת תג
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