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DIDS modifies the conductance, gating, and inactivation mechanisms of the cardiac ryanodine receptor.

The effects of the covalent modifier of amino groups, 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS) on the single-channel properties of purified sheep cardiac ryanodine receptors (RyR) incorporated into planar phospholipid bilayers were investigated. DIDS increased single-channel...

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Detalles Bibliográficos
Main Authors: Hill, Adam Parker, Sitsapesan, Rebecca
Formato: Artigo
Idioma:Inglês
Publicado: 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302091/
https://ncbi.nlm.nih.gov/pubmed/12023226
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