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Structural factors that determine the ability of adenosine and related compounds to activate the cardiac ryanodine receptor
1. The effects of adenosine and adenine on the gating of native sheep cardiac ryanodine receptor (RyR) channels were investigated. By examining the mechanisms underlying channel activation and by using comparative molecular field analysis (CoMFA) we have investigated the structural features of adeni...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572218/ https://ncbi.nlm.nih.gov/pubmed/10928966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703459 |
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