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The key event in force-induced unfolding of Titin's immunoglobulin domains.

Steered molecular dynamics simulation of force-induced titin immunoglobulin domain I27 unfolding led to the discovery of a significant potential energy barrier at an extension of approximately 14 A on the unfolding pathway that protects the domain against stretching. Previous simulations showed that...

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Detalles Bibliográficos
Main Authors: Lu, H, Schulten, K
Formato: Artigo
Idioma:Inglês
Publicado: 2000
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300915/
https://ncbi.nlm.nih.gov/pubmed/10866937
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