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Functional analysis of myosin mutations that cause familial hypertrophic cardiomyopathy.

We have studied the actin-activated ATPase activities of three mutations in the motor domain of the myosin heavy chain that cause familial hypertrophic cardiomyopathy. We placed these mutations in rodent alpha-cardiac myosin to establish the relevance of using rodent systems for studying the biochem...

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Detalhes bibliográficos
Main Authors: Roopnarine, O, Leinwand, L A
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1299973/
https://ncbi.nlm.nih.gov/pubmed/9826622
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