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Mice expressing mutant myosin heavy chains are a model for familial hypertrophic cardiomyopathy.

BACKGROUND: Familial hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease characterized by ventricular hypertrophy, myocellular disarray, arrhythmias, and sudden death. Mutations in several contractile proteins, including cardiac myosin heavy chains, have been described in families wit...

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Detalhes bibliográficos
Main Authors: Vikstrom, K. L., Factor, S. M., Leinwand, L. A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Feinstein Institute for Medical Research 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230192/
https://ncbi.nlm.nih.gov/pubmed/8898372
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