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D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a

The protein kinase CK1 phosphorylates serine residues that are located close to another phosphoserine in the consensus pSer-Xaa-Xaa-Ser. This specificity generates regions in its target proteins containing two or more neighbouring phosphoserine residues, termed here multisite phosphorylation domains...

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Detalhes bibliográficos
Main Authors: Rena, Graham, Bain, Jenny, Elliott, Matthew, Cohen, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1298959/
https://ncbi.nlm.nih.gov/pubmed/14710188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400048
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