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Elevated nuclear Foxo1 suppresses excitability of skeletal muscle fibers

Forkhead box O 1 (Foxo1) controls the expression of proteins that carry out processes leading to skeletal muscle atrophy, making Foxo1 of therapeutic interest in conditions of muscle wasting. The transcription of Foxo1-regulated proteins is dependent on the translocation of Foxo1 to the nucleus, whi...

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Main Authors: Hernández-Ochoa, Erick O., Schachter, Tova Neustadt, Schneider, Martin F.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761173/
https://ncbi.nlm.nih.gov/pubmed/23804205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00003.2013
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