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The function of FOXO1 in the late phases of the cell cycle is suppressed by PLK1-mediated phosphorylation
Polo-like kinase 1 (PLK1) plays crucial roles in multiple stages of cell division. Our previous studies suggest that global transcriptional regulation by PLK1 may contribute to its multiple functions. PLK1 depletion is associated with a decrease in cell viability and the induction of apoptosis; howe...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979917/ https://ncbi.nlm.nih.gov/pubmed/24407358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27727 |
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