Suppression of Vimentin Phosphorylation by the Avian Reovirus p17 through Inhibition of CDK1 and Plk1 Impacting the G2/M Phase of the Cell Cycle

The p17 protein of avian reovirus (ARV) causes cell cycle retardation in a variety of cell lines; however, the underlying mechanism(s) by which p17 regulates the cell cycle remains largely unknown. We demonstrate for the first time that p17 interacts with CDK1 and vimentin as revealed by reciprocal...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chiu, Hung-Chuan, Huang, Wei-Ru, Liao, Tsai-Ling, Wu, Hung-Yi, Munir, Muhammad, Shih, Wing-Ling, Liu, Hung-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014334/
https://ncbi.nlm.nih.gov/pubmed/27603133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162356
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