Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2

Protein kinase D2 (PKD2), a member of the PKD family of serine/threonine kinases, is localized in various subcellular compartments including the nucleus where the kinase accumulates upon activation of G-protein-coupled receptors. We define three critical post-translational modifications required for...

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Detalhes bibliográficos
Main Authors: von Blume, J, Knippschild, Uwe, Dequiedt, Franck, Giamas, Georgios, Beck, Alexander, Auer, Alexandra, Van Lint, Johan, Adler, Guido, Seufferlein, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080801/
https://ncbi.nlm.nih.gov/pubmed/17962809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601891
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