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Role of the Regulatory Domain of Protein Kinase D2 in Phorbol Ester Binding, Catalytic Activity, and Nucleocytoplasmic Shuttling

Protein kinase D2 (PKD2) belongs to the PKD family of serine/threonine kinases that is activated by phorbol esters and G protein-coupled receptors (GPCRs). Its C-terminal regulatory domain comprises two cysteine-rich domains (C1a/C1b) followed by a pleckstrin homology (PH) domain. Here, we examined...

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Detalhes bibliográficos
Main Authors: Auer, Alexandra, von Blume, Julia, Sturany, Sabine, von Wichert, Götz, Van Lint, Johan, Vandenheede, Jackie, Adler, Guido, Seufferlein, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196345/
https://ncbi.nlm.nih.gov/pubmed/15975900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-03-0251
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