Lack of MSH2 involvement differentiates V(D)J recombination from other non-homologous end joining events

V(D)J recombination and class switch recombination are the two DNA rearrangement events used to diversify the mouse and human antibody repertoires. While their double strand breaks (DSBs) are initiated by different mechanisms, both processes use non-homologous end joining (NHEJ) in the repair phase....

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Bibliographic Details
Main Authors: Larijani, Mani, Zaheen, Ahmad, Frieder, Darina, Wang, Yuxun, Wu, Gillian E., Edelmann, Winfried, Martin, Alberto
Format: Artigo
Language:Inglês
Published: Oxford University Press 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1297709/
https://ncbi.nlm.nih.gov/pubmed/16314305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki983
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