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Lack of MSH2 involvement differentiates V(D)J recombination from other non-homologous end joining events

V(D)J recombination and class switch recombination are the two DNA rearrangement events used to diversify the mouse and human antibody repertoires. While their double strand breaks (DSBs) are initiated by different mechanisms, both processes use non-homologous end joining (NHEJ) in the repair phase....

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Hlavní autoři: Larijani, Mani, Zaheen, Ahmad, Frieder, Darina, Wang, Yuxun, Wu, Gillian E., Edelmann, Winfried, Martin, Alberto
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1297709/
https://ncbi.nlm.nih.gov/pubmed/16314305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki983
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