Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes

Histone deacetylases (HDACs) are thought to function as critical mediators of transcriptional repression. However, the physiological targets and posttranslational modifications of the class II HDACs are largely unknown. Here we show that the C terminus of HDAC 6 is both necessary and sufficient for...

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Publikašuvnnas:	Proc Natl Acad Sci U S A
Váldodahkkit:	Hook, Sara S., Orian, Amir, Cowley, Shaun M., Eisenman, Robert N.
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	National Academy of Sciences 2002
Fáttát:	Biological Sciences
Liŋkkat:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129689/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12354939/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.172511699
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