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Physical constraints and functional characteristics of transcription factor–DNA interaction

We study theoretical “design principles” for transcription factor (TF)–DNA interaction in bacteria, focusing particularly on the statistical interaction of the TFs with the genomic background (i.e., the genome without the target sites). We introduce and motivate the concept of programmability, i.e.,...

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Hlavní autoři: Gerland, Ulrich, Moroz, J. David, Hwa, Terence
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC129390/
https://ncbi.nlm.nih.gov/pubmed/12218191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192693599
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