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Physical constraints and functional characteristics of transcription factor–DNA interaction

We study theoretical “design principles” for transcription factor (TF)–DNA interaction in bacteria, focusing particularly on the statistical interaction of the TFs with the genomic background (i.e., the genome without the target sites). We introduce and motivate the concept of programmability, i.e.,...

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Bibliografske podrobnosti
Main Authors: Gerland, Ulrich, Moroz, J. David, Hwa, Terence
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC129390/
https://ncbi.nlm.nih.gov/pubmed/12218191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192693599
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